NAD+
ALSO SOLD AS Nicotinamide adenine dinucleotide
Last reviewed 2026-10-30
Our read Opinion
Small human metabolism studies and a registered comparative trial exist, without established anti-aging efficacy. FDA reports adverse reactions to compounded injectables consistent with endotoxin contamination.
- Type
- Research-only / unapproved
- Regulatory status
- No FDA-approved NAD+ wellness therapy identified
- Compounding status
- Compounded by pharmacies (verify)
- FDA-approved indications
- None
- Evidence level
- Small/early human studies
- Routes studied
- —
- WADA
- Verify
- Developer
- —
Claims made by researchers, companies and users. Inclusion does not mean the claim is verified.
- —Claimed to support cellular energy
NAD+ is an electron carrier in energy metabolism and a substrate for enzymes including sirtuins and PARPs. Its essential physiological role does not establish benefit from administering additional NAD+.
Not a peptide: NAD+ is a coenzyme involved in cellular redox reactions and signaling. No FDA-approved NAD+ anti-aging or wellness indication was identified; supplement status does not authorize an injectable drug.
Statuses change; check the linked primary source.
Momentum Opinion
Rising
0 news items in last 30 days
NAD+ biology is important, but wellness claims require intervention-specific clinical outcomes. Evidence on precursors such as NR should not be substituted for evidence on NAD+ itself.
No news yet for this peptide.
Better cellular energy, endurance and 'mitochondrial aging' support.
Information only. Not medical advice. Listing a compound is not an endorsement or a recommendation to obtain or use it. Ratings and "Our Take" are editorial opinion. Full disclaimer.