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Up to four peptides. Opinion rows are labeled. Copy the URL to share.
| Field | GHK-Cu | AHK-Cu |
|---|---|---|
| Type | Cosmetic / Supplement | Cosmetic / Supplement |
| Regulatory status | Cosmetic ingredient; not FDA-approved as a drug | Cosmetic/research ingredient; no FDA-approved drug |
| Compounding status | Off Category 2, review pending | Unclear / not listed |
| FDA-approved indications | None | None |
| Categories | Skin & cosmetic, Longevity & mitochondrial | Skin & cosmetic |
| Claimed uses |
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| Mechanism | A copper-binding tripeptide investigated for extracellular-matrix remodeling, collagen production and wound-repair signaling. Much of the broad regenerative mechanism literature is preclinical. | An alanine-histidine-lysine copper complex studied for dermal papilla cell proliferation and hair-follicle elongation. Evidence comes from cultured cells and isolated human follicles, not clinical hair-regrowth trials. |
| Evidence level | Small/early human studies | In vitro / theoretical |
| Evidence / Hype (opinion) | Evidence Hype | Evidence Hype |
| Momentum (opinion) | Rising | Watch |
| Routes | Topical, Injection | Topical |
| WADA | Verify | Verify |
| Where it stands (opinion) | Topical cosmetic evidence and experimental tissue-repair findings do not validate systemic use. FDA lists injectable GHK-Cu among withdrawn nominations with unresolved safety concerns. | A published ex vivo/in vitro study supports a laboratory hair-growth hypothesis. Clinical effectiveness and injectable safety remain unestablished; US bulk-compounding eligibility was not verified. |
| Last reviewed | 2026-10-30 | 2026-10-30 |
| News (30d) | 1 | 0 |