Peptide/Health/News

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FieldBPC-157
KPV
TypeResearch OnlyResearch Only
Regulatory statusNot FDA-approved; no verified marketing authorizationNot FDA-approved; no verified marketing authorization
Compounding statusOff Category 2, review pendingOff Category 2, review pending
FDA-approved indicationsNoneNone
CategoriesHealing & repair, GIGI, Healing & repair
Claimed uses
  • — Claimed to support tendon, gut and tissue repair
  • — Claimed to support gut lining repair
  • — Claimed to calm inflammation
MechanismSynthetic pentadecapeptide studied for tissue repair, angiogenesis and nitric-oxide signaling. Proposed mechanisms largely derive from animal and cell experiments.Lys-Pro-Val is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone. In cell and mouse models, PepT1-mediated uptake inhibits inflammatory NF-kappaB and MAPK signaling.
Evidence levelAnimal studies mostlyAnimal studies mostly
Evidence / Hype (opinion)
Evidence
Hype
Evidence
Hype
Momentum (opinion)RisingRising
RoutesInjection, OralOral, Topical
WADAProhibitedVerify
Where it stands (opinion)FDA now places BPC-157 in its withdrawn-nomination table, not the active Category 2 table; this is not compounding authorization. WADA 2026 S0 prohibits BPC-157.Evidence remains preclinical, including mouse colitis models. FDA moved KPV to its withdrawn-nomination table; this is not authorization for compounding.
Last reviewed2026-10-302026-10-30
News (30d)30